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Study number 8548-638

Screening Now!

Dates

Sep 08 2025-Nov 04 2025

Location

Madison, Wisconsin

Age

18-55

Gender

Male and Female

Smoker

No

Compensation

$8,378

Group

B2a

Study Details

The investigational drug in this research is being developed for the potential treatment of plycythemia vera, which, is a certain kind of cancer where the body produces too many red blood cells. 

Women Eligibility Criteria

  • Must be of non-childbearing potential due to:
    • Age 40+ and post-menopausal for 1 year, OR
    • Surgically sterile due to one of the following procedures:
      • Hysterectomy
      • Bilateral salpingo-oophorectomy
      • Bilateral salpingectomy
      • Bilateral oophorectomy

Body Mass Index (BMI)

  • Participants should have a BMI of: 18-32

Smoking Criteria

  • Participants who are smokers must:
    • No smoking 3 months prior to check-in. 

Medication Restrictions

  • Participants should not be using:
    • Weight loss medications
    • Insulin (currently or in the past 3 months)

Screening Procedures

  • Screening procedures for this study may include:
    • Vitals
    • Physical examination
    • Electrocardiogram (ECG)
    • Lab testing for HbA1c
    • Drug and alcohol testing

Additional Details

B2a:

Check-in: Sep 8

Check-out: Sep 11

Check-in: Sep 15

Check-out: Sep 16

Check-in: Oct 6

Check-out: Oct 7

Check-in: Nov 3

Check-out: Nov 4

Follow-up Visits: Sep 23, Oct 21

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